IITC Plantar Test Hargreaves Method for Mice and Rats

Plantar Test Apparatus (Hargreaves Method) for Mice and Rats

The IITC Plantar Analgesia Meter for thermal paw can be used on 12 mice, 6 rats and other animals (cats, rabbits) unrestrained when testing for narcotic drugs. Experiments are easy to perform, simply slide the test head under test subject, align the heat source via our exclusive guide light (idle state) by the attached, adjustable, angled mirror on test head to test subject and perform tests.

Supplied complete as shown with animal enclosures

Category: Analgesia Equipment Tag: Analgesia Equipment

Features

Precise programmable digital control
Humane cut-off feature
Adjustable beam intensity in 1% increments room temperature to 250 degrees c.
Manual override of all timer functions
Alphanumeric readout
All Functions and parameters entered via key-pad
Heated glass option only from IITC
Footswitch – RS232 – Printer output (standard)
Software – USB – (optiona

Description

SuperGear

Part #	Description
390	Plantar Test (Hargreaves method)
390G	Plantar Test (Hargreaves method) with heated glass
433	Animal Enclosure for Plantar Test (4 mice 2 rats)
435	Animal Enclosure for Plantar Test(12 mice 6 rats)
Series 8	Software

Details

Start, stop and reset of tests is done by either the pushbutton on test head, front panel controls or supplied footswitch.

With our exclusive “idle state” of the heat source one is assured of exact placement of the heat source as well as mirror which is placed on top of heat source. Tests are performed on the plantar surface by a focused, radiant heat light source. The light beam is focused to the top of the glass and creates a 4X6mm intense spot on the paw.

Our method of visible light is superior to the infrared light method, since a user will not always know exactly where/when the test will start, causing false starts and conditioning of animals. A built-in timer displays reaction time in .01 second increments.

The height of the glass is adjustable allowing the focal point of the light to be adjusted to stimulate other body parts if needed. A Humane cutoff timer is standard. The unit can be preset for a cutoff period, at the end of which the heat source shuts off automatically if the animal has not responded, avoiding tissue damage. Our test head does not emit , clicking or whining noises that cause preconditioning of animals prior to test as with other systems on the market.

Our exclusive heated glass option eliminates the glass acting as a heat sink. This feature will eliminate the reaction time of the animals to be altered due to the fact that they are placed on cold glass allowing the possibility of delayed response time to the applied heat source. Built-in heating elements in the glass which are digitally controlled for consistent temperatures. Temperature readout and adjustment from 30-40 degrees c. for the heated base is controlled on the heated base.

Three individual, acrylic animal enclosures are supplied. Each enclosure allows for 2 rats/4 mice allowing testing of up to 6 rats/12mice total. Enclsoures have strong magnets to prevent animals from possible escape., individual lids, clear dividers in-between test subjects.

Animal Enclosure

Specs

390(G) Plantar Test Analgesia Meter for mice and rats

Footprint: 12” x 12” x 5”

Equipment Material: Powder coated aluminum

Test Head with mirror: 5 1/4″ x 4 ¼” x 5 ½”

Detection: User

Heat Source: Halogen bulb, 150w/24v

Footprint heated base: 30” x 13 ¾” x 4 ¼”

Footprint non-heated base: 30 ½” x 13 ¾” x ½”

Base Material: Powder coated aluminum

Heated Glass – 30 ½” x 12 ½” x 1/2”

Non-heated Glass – 30 ½” x 12 ½” x ¼”

Animal Enclosure inside dims.: Mouse 4” x 4” – Rat 8” x 4”

Switchable: 110/220V

3 Amp.

Series 8 Software: Windows

CE Certified

Articles

A rat model of bone cancer pain induced by intra-tibia inoculation
of Walker 256 mammary gland carcinoma cells

P-selectin is required for neutrophils and macrophage infiltration
into injured site and contributes to generation of behavioral
hypersensitivity following peripheral nerve injury in mice

A sensory subpopulation depends on vesicular
glutamate transporter 2 for mechanical pain, and
together with substance P, inflammatory pain

Nociception before and after exercise in rats bred for high
and low aerobic capacity

The effect of morphine on MC4 and CRF receptor mRNAs in the rat
amygdala and attenuation of tolerance after their blockade

A rat model of bone cancer pain induced by intra-tibia inoculation
of Walker 256 mammary gland carcinoma cells

Behavioural signs of chronic back pain in the SPARC-null
mouse

Forebrain overexpression of CaMKII abolishes cingulate long term
depression and reduces mechanical allodynia and thermal
hyperalgesia

The effect of morphine on MC4 and CRF receptor mRNAs in the rat
amygdala and attenuation of tolerance after their blockade

Software

The IITC Series 8 software is available for each Series 8 unit. The individual software will capture data in real-time from one of the units and can be exported into Excel or other spreadsheet programs.

Data supplied:
Test
Animal number
Date
Time
Duration
Temperature
Starting temperature
Stop temperature
Set point temperature
Active intensity
Idle intensity
Cut off time
Reaction time
Top end speed
Distance

The data supplied will depend on which Series 8 equipment is used with the corresponding software.