IITC Tail Flick Test Analgesia Meter for Mice and Rats

Features

Description

An overhead halogen light source is in a constant “ON” (idle state). A pre-focused heat source supplies an area of 4X6mm stimulation to the tail. A built-in sensor in the tail groove detects the tail flick of the animal. The tail groove is a non-metallic material to avoid unnecessary conditioning of your animals; unlike other systems. If the animal does not flick their tail within the pre programmed cut-off time; the heat source shuts off automatically; avoiding tissue damage. Built-in timer displays the reaction time in 0.01 second increments. Control of system can be from either the front panel or supplied footswitch: Start, Stop and Reset of tests. TAIL TEMPERATURE OPTION (T)Tail Temperature Probe Measurement of tail temperature at all times.  Trigger temperature is automatic at start of every test. Warms tail to preset temperature (set by user) and then tests start, allowing all tail temperatures to be identical.  This optional feature allows automatic preheating of the tail up to 75 degrees c., ensuring all experiment protocols to be precisely controlled and repeated. Once a preset temperature is reached, the test and timer start automatically. Once the animal reacts via tail flick the timer and heat source stop and test results are displayed. Readout will now show in repeatable sequence, start , end temperatures and test time. This unique feature stores the set temperature unless otherwise changed; eliminating temperature variations from test to test. We recommend that animals be restrained with one of the IITC restrainers.  This unit solves the problem associated with “tail temperature prior to and at the end of testing.” See article: KJELL HOLE AND ARNE TJOLSEN: The Tail-Flick Formalin Test in Rodents: Changes in Skin Temperature as a Confounding Factor. Pain 53 (1993) pages. 247-254 Elsevier).

Specs

33 Tail Flick Analgesia Meter for Mice and Rats

Footprint: 12” x 12” x 5”

Equipment Material: Powder coated aluminum

Tail Groove: Mice and rats

Test Head: 5 1/4″ x 4 ¼” x 5 ½”

Detection: Photoelectric (Automatic, humane cut-off)

Heat Source: Halogen bulb, 150w/24v

Switchable: 110/220V

3 Amp.

Series 8 Software: Windows

CE Certified

Articles

Evaluation of the Antinociceptive Activity and Acute OralToxicity of Standardized Ethanolic Extract of the Rhizome ofCurcuma xanthorrhiza RoxbAnti-inflammatory and Analgesic Effect of Plumbagin throughInhibition of Nuclear Factor-B ActivationThe evaluation of antinociceptive activity of alkaloid, methanolic, and aqueousextracts of Malaysian Mitragyna speciosa Korth leaves in ratsTolerance to non-opioid analgesics is opioid sensitive in thenucleus raphe magnusTRPM8 is the principal mediator of menthol-induced analgesia of acuteand inflammatory painA role for adrenomedullin as a pain-related peptidein the rat

Software

The IITC Series 8 software is available for each Series 8 unit. The individual software will capture data in real-time from one of the units and can be exported into Excel or other spreadsheet programs.

Data supplied:
Test
Animal number
Date
Time
Duration
Temperature
Starting temperature
Stop temperature
Set point temperature
Active intensity
Idle intensity
Cut off time
Reaction time
Top end speed
Distance

The data supplied will depend on which Series 8 equipment is used with the corresponding software.

FAQ's