IITC Hot Cold Plate Analgesia Meter for Mice and Rats

 

The original Cold Hot Plate Test available with ramping temperature from -10 deg. C to 70 deg. C.

IITC Life Science developed the first commercially available Cold Hot Plate test appratus in the world which is capable of truly assessing pharmacological modulation of thermonociception. Used on latency and threshold based nociception for both conventional and non conventional analgesics a safe and humane way of testing.

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Features

  • Cold/Hot Plate 0 – 70 degrees Celsius
  • Ramping temperature for threshold & latency results
  • Rapid increase or decrease in temperature
  • Supplied with a clear animal enclosure
  • Plate size 4” x 8”
  • Precise Programmable digital control
  • Print out of data
  • Temperature stability is .1 deg. C.
  • Footswitch
  • Software – USB – (optional)

Description

Part # Description
PE34 Cold Hot Plate Analgesia Meter Apparatus for mice and rats
Series 8 Software
PE34E Hot Cold Plate Analgesia Meter Animal Enclosure

Details

As published in the British Journal of Pharmacology-

Almasi et al: Effect of resiniferatoxin on the noxious hear threshold temperature in the rat: A novel heat allodynia model sensitive to analgesics. 139(1):49-58, 2003, British Journal of Pharmacology

 

IITC’s Hot Cold Plate is used to measure the nociceptive threshold of analgesic compounds in mice and rats. Conventional constant temperature hot plate tests only measure latencies of stronger narcotic agents.

IITC’s Hot/Cold Plate Analgesia Meter widens the range of analgesia research to new levels. The unit is microprocessor controlled and can be used for both incremental heating and cooling from any starting temperature from 0 deg. c. to 70 deg. c in 0.1 degrees c. increments. The microprocessor monitors and controls the rate of heating/cooling which can be set from 1 to 10 deg c. per minute. The front panel display shows all test results including length of test in .01 sec. increments, starting temperature and stopping temperature. The plate is uniformly heated/cooled at an adjustable rate and has automatic upper/lower cut-off limits. All parameters are entered via front panel keypad. i.e. rate of temperature increase/decrease, maximum/minimum temperature, date/time and animal number.

The IITC system can also double as a constant temperature hot plate analgesia meter.

Temperature stability is .1 deg. c.

Upon reaction of either the hind or forepaw (whichever is chosen) the heating/cooling of the unit is reversed to the standby temperature within minutes. The data includes the date, animal number, temperature and time of day. The readout updates the controlled parameters.

Specs

PE34 Hot/Cold Plate Analgesia Meter for Mice and Rats

Footprint: 18” x 18” x 5”

Equipment Material: Powder coated aluminum

Hot/Cold Plate material:  Aluminum

Hot/Cold Plate dims. :  4” x 8”

Animal Enclosure Material: Plexi-Glas

Animal Enclosure dia: 4” x 8”

Temperature range:  0 to 65 deg. C (may be ordered -5/-10 deg. C), (.1 deg. C increments)

Switchable: 110/220V

8 Amp.

Series 8 Software:  Windows

CE Certified

Software

The IITC Series 8 software is available for each Series 8 unit. The individual software will capture data in real-time from one of the units and can be exported into Excel or other spreadsheet programs.

Data supplied:
Test
Animal number
Date
Time
Duration
Temperature
Starting temperature
Stop temperature
Set point temperature
Active intensity
Idle intensity
Cut off time
Reaction time
Top end speed
Distance

The data supplied will depend on which Series 8 equipment is used with the corresponding software.

Part # Description

Series 8

 Series 8 Software for Analgesia Equipment

FAQ's

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