Incremental Hot & Cold Plate Analgesia Meter for Mice and Rats

Only unit in the world capable of truly assessing pharmacological modulation of thermonociception. Used on latency and threshold based nociception for both conventional and nonconventional analgesics. A safe and humane way of testing with true extreme temperature ranges for cold allodynia hyperalgesia as well as hot. Our Hot Cold Plate Analgesia Meter finally allows researchers to accurately test extreme hot and cold temperatures for pain research.

 

  • 0 deg. C to 70 deg. C
  • Rapid (ramping) increase or
  • decrease in temperature set by experimenter
  • Precise Programmable digital control
  • Temperature stability is .1 deg. C.
  • RS232 Standard
  • Printer output standard
  • Footswtich standard
  • Software for data collection (optional)
  • Thermal printer (optional)

The IITC Life Science Incremental Hot Cold Plate Analgesia Meter exclusive. This unit is used to measure the nociceptive threshold of analgesic compounds in mice and rats.

The conventional constant temperature HotPlate tests only latencies of stronger narcotic agents. The constant temperature Hot Plate cannot be used for increasing Hot Plate tests since the cooling is too long and is unsuitable for repeated tests. Therefore, the IITC Incremental Hot Cold Plate widens the range of analgesia research to new levels.

The unit is microprocessor controlled and can be used for both incremental heating and cooling from any starting temperature from 0 deg. C. to 70 deg. C in 0.1 degrees C increments.

The microprocessor monitors and controls the rate of heating/cooling which can be set from 1 to 10 deg C per min. The front panel display shows all test results including length of test in .01 sec. increments, starting temperature and stopping temperature.

Temperature stability is .1 deg. C.

The plate is uniformly heated/cooled at an adjustable rate and has automatic upper/lower cut-off limits. All parameters are entered via front panel keypad. i.e. rate of temp increase/decrease, maximum/minimum temp, date/time and animal number.

Upon reaction of either the hind or forepaw (whichever is chosen) the heating/cooling of the unit is reversed to the standby temperature within minutes. The data includes the date, animal number, temperature and time of day. The readout updates the controlled parameters. An animal cover and footswitch is supplied.

The unit is supplied with a clear animal enclosure. Plate size 4" x 8". The unit can also double as a constant temperature hot plate analgesia meter.

Part #

PE34 Incremental Hot Cold Plate Analgesia Meter for mice and rats

Dimensions:
17" X17" X 5.25"
Animal Enclousure 7.625" X 3.625" X 5"

Two year warranty and CE Certified

Partial List of Literature References:

Investigation of the role of TRPV1 receptors in acute and chornic nociceptive processes using gene-deficient mice,
Pain 117 (2005) 368-376

Effect of resiniferatoxin on the noxious hear threshold temperature in the rat: A novel heat allodynia model sensitive to analgesics.
139(1):49-58, 2003, British Journal of Pharmacology


More Literature referenfces upon request



IITC Life Science Inc.
23924 Victory Blvd Woodland Hills, CA 91367
818 710 8843 fax 818 992 5185
 
  Copyright (c) 2007. IITC Life Science
All rights reserved.