The Original Electronic von Frey Anesthesiometer IITC Life Science

Our electronic unit now has the capability of testing the Electronic von Frey method, Plethysmometer (Paw Volume) and the Randall Selitto test; all test results digitally recorded with one simple easy to use unit. No longer is "The up down method" necessary.

IITC introduced the Electronic Von Frey Aesthesiometer over 9 years ago, now the standard for pain and sensory measurements. A patented solution to paw pressure threshold measurements. Copied by many but this is the original with many published papers (see a few below, contact us for more).

NEW LIMIT INDICATOR -

With the newest addition to the IITC Life Science Electronic von Frey Anesthesiometer you can preset and select for each test the force limit that one would like to employ within 1 gram of accuracy! A warning light will inform the user when the limit that is preset by the user has been reached.

Now identical results from two different operators with this new feature.

Available in two forms -

1. Independent cable with red LED warning light at the tip - Connects to any existing 2390 unit (not available for 2290 series). Plug in, simple digital preset

2. Ordered built-into the 2390 probe. Limit indicator light is at the tip of probe within direct view of operator. Wide angle LED used. Probe can be ordered without LED.

MRI Probe available
Plug 3 probes into a single unit
LCD Readout (Floating or last max. & minimum
Rigid tips up to 800 Gr.
"Supertips™ .01 up to 90 Gr.
1000 gram probe available
RS-232 output
Microprocessor Electronics 0.1 Gr Plug-in probes
Independence from Hygroscopy
Independence from temperature
Supplied w/battery and line adapter
Optional analog output available upon request

Simple to use: All that is required is to apply pressure to the subject and upon reaction the system will automatically record and display the force applied (force shown in grams). The system will display current reading, maximum hold reading.

This unit finally eliminiates the need to to manually calculate test results when measuring either with the flexible von Frey hairs or with the rigid tips. Tips are reusable and additional can be ordered. A clean efficinet system for anyone looking to measure allodynia on any test subject today.

Scroll down for further information.

Mesh Stands for your Electronic von Frey Anesthesiometer:

The mesh stands with 16" legs for ease of viewing when doing the von Frey test.

Rigid Tip.8mm Supertip®

Semi Flexible (Hygroscopy Free)

The supplied tips are made of nylon or polyproplyene, and mount on the probe exactly as the pipette tips.

What are "Supertips™
As reported by earlier papers varying probe diameter on Von Frey hairs is a serious problem. These patented “Supertips™” have a UNIFORM TIP DIAMETER 0F .8mm ON ALL 15 DIFFERENT VON FREY HAIRS! This is a unique feature available only on electronic von Freys by IITC Life Science. Probe size no longer affects pain or pressure thresholds and results are comparable!

This instrument eliminates the poor data collection due to the hygroscopic nature of Von Frey hairs (it is proven that relative humidity can change the force by more than 100% between 28-52% relative humidity change!) Only an accurate readout can show the actual force, not a number on the handle on classic Von Frey handles. Bending at various degrees can change the force by 20-30% in every case, this is visible with an electronic readout only. The natural limiting of force with flexible hairs is of great advantage. This instrument makes the up-down method of finding threshold unnecessary. Battery life is 50 hours. (supplied)

Part #

2390 Electronic von Frey rigid tips only, 90 gram range

2391 Electronic von Frey rigid tips only, 800 gram range

2392 Electronic von Frey rigid and 15 Supertips, 90 gram range

2393 Electronic von Frey rigid and 15 Supertips, 800 gram range

2394 Probe only, 90 gram range

2395 Probe only, 800 gram range

One Year Warranty and CE Certified

Literature Reference:

1. Effects on Birth Weight and Adult Health in Rats Prenatally Exposed to Toxicants or Undernutrition.
Brain E. Grey, Brenda Barbee, Kaberi Das, Joel Norwood, Christopher Lau, and John M. Rogers.
Reproductive Toxicology Division, NHEERL, ORD, U.S. Environmental Protection Agency, Research Triangle Park, NC
Poster Presented at SOT 2007

2. Deep tissue inflammation upregulates neuropeptides and evokes nociceptive behaviors which are modulated by a neuropeptide antagonist
Ranjinidevi Ambalavanar, Masayuki Moritani, Aicha Moutanni, Panduranga Gangula, Chandrasekha Yallampalli, Dean Dessem
Pain 120 (2007) 53-68

3. Evaluation of a von Frey Device for Pharmacoddynamic Modeling of Morphine in Dogs.
Butch KuKanich, B. Duncan X. Lascelles, Mark G. Papich
Comparatrive Pain and Pharmacology Research Laboratories

4. An electronic pressure-meter nociception paw test for rats
G.G. Vivancos, W.A. Verri Jr, T.M. Cunha, I.R.S. Schivo, C.A. Parada,
F.Q. Cunha and S.H. Ferreira
Brazilian Journal of Medical and Biological Research (2004) 37:391-399

5. An electronic pressure-meter nociception paw test for rats
G.G. Vivancos, W.A. Verri Jr, T.M. Cunha, I.R.S. Schivo, C.A. Parada,
F.Q. Cunha and S.H. Ferreira
Brazilian Journal of Medical and Biological Research (2004) 37:401-407

6. Assessment of von Frey device for evalution of the antinociceptive effects of morphine and its application in pharmacodynamic modeling of morphine in dogs
Butch KuKanich, DVM, PhD; B. Duncan X. Lascelles, BVSc, PhD; Mark G. Papich, DVM, MS
American journal of Veterinary Research 2005 66(9).

7. Cairns BE, Gambarota G, Svensson P, Arendt-Nielsen L, Berde CB. Glutamate-induced sensitization of rat masseter muscle fibers. Neuroscience, 2002; 109: 389-399.

8. Arpad Dobolyi, Hiroshi Ueda, Hitoshi Uchida, Miklos Palkovits, and Ted B. Usdin, Anatomical and physiological evidence for involvement of tuberoinfundibular peptide of 39 residues in nociception. , , PNAS, February 5, 2002, volume. 99, no. 3, 1651 to 1656

9. Jensen K. Andersen et al: Pressure-Pain threshold In Human Temporal Region. Evaluation of A New Pressure Algometer Pain, 1986;25:313-23. (This is why"SupertipsTM" exist!) Poster at IASP Congress San Diego 2002

10. 437-P71 Performance of Von frey polyamide Monofilaments During Changes in relative Humidity: A Calibration Study. Per R. Neilsen, Mads U. Werner, Catarina Ellehuus. Dept Anesthesiology, Univ Hospital, Hvidovre, Denmark (spon: Per R. Nielsen)

11. Assessment of Stimulation Parameters Used In Measuring Mechanical Hyperalgesia In Animal Models Of Pain. Harry J. Gould, III, R. Denis Soignier, Porter Nolan, Sarah J. Vitale, and Dennis Paul. Departments of Neurology and Pharmacology, and Neuroscience Center of Excellence LSU Health Sciences Center, New Orleans, LA, USA 70112

12. Abstract: Validation of an Electronic Von Frey Device in a Rat Model of Incisional Pain and its use in Assessing the Efficacy of Clinically Relevant Analgescis. L. Mark; G. Whiteside, J. Boulet, K. Walker., Discovery Research, Purdue Pharma, Cranbury, NJ, USA (presented at SFN 2003)