Rotarod Test Rats and Mice

• No adjustments required on sensing platforms
• Digitally controlled
• Five (5) lanes standard
• Adjustable test length
• Adjustable start speed
• Adjustable top end speed
• Adjustable ramp speed
• Forward and reverse rotation mode
• Distance recorded in Meters
• Footswitch
• Software – optional

Part # Description

755 Rotarod Treadmill for mice and rats

Series 8 Software

IITC’s Rotarod Test has the capabilities of having up to five mice or rats tested at a time standard.

The user can select from one to five lanes to be included in an experiment. For mice experiments 1¼ inch diameter drums are supplied and for rat experiments 3¾ inch diameter drums are supplied. All that is needed is a standard Philips screwdriver to change the drums, no other tool required.

The LED display shows all test results for each animal position; they are: Stopping RPM, length of test and distance traveled.

Animals drop is sensed by accurate magnetic switches that never need adjusting versus other units on the market today which use photoelectric sensing. Vertically sliding acrylic front panels prevent escape of animals.

Literature Reference: Jones & Roberts, F. Pharm., Pharmacol., 1968, 20, 302

The electronic gear is built into the base of the unit. All parameters are digitally controlled and entered via the keypad on the front panel. Start, stop and reset buttons are also on the front of the unit. An LED display allows the user to view all parameters and test results.

Key features of the IITC Rotarod are the following:

Adjustable test length: 1 to 999 seconds.
Adjustable start speed: 0 to 45 RPM’s.
Adjustable top end speed: 45 RPM’s.
Adjustable ramp speed: 0 to 999 seconds.
Forward, reverse mode
Distance recorded in Meters

Two year warranty
120/240V
CE

Acute Inhibition of Ca2
/Calmodulin-Dependent Protein Kinase
II Reverses Experimental Neuropathic Pain in Mice

Exposure to an Environmental Neurotoxicant Hastens the Onset of ALS-Like Phenotype
in hSOD1G93A Mice: Glutamate-Mediated Excitotoxicity

Resveratrol treatment in mice does not elicit the bradycardia and hypothermia
associated with calorie restriction

Loss of Quinone Reductase 2 Function Selectively Facilitates
Learning Behaviors

Substitution of a mutant a2a-adrenergic receptor via ‘‘hit and
run’’ gene targeting reveals the role of this subtype in sedative,
analgesic, and anesthetic-sparing responses in vivo

Defective Fas expression exacerbates
neurotoxicity in a model of Parkinson’s disease

Resveratrol treatment in mice does not elicit the
bradycardia and hypothermia associated with calorie
restriction

Mice Expressing the A53T Mutant Form of Human Alpha-
Synuclein Exhibit Hyperactivity and Reduced Anxiety-Like
Behavior

TRPM8 is the principal mediator of menthol-induced analgesia of acute
and inflammatory pain

• Am I able to test both mice and rats with one Rotarod system?

Yes, no other items are required to enable testing of both mice and rats.

• How does the Rotarod system record the tests?

The animals are placed on the drums and the system is started, once the animals fall onto the platforms below the platforms trigger the electronics which in turn shut down for that individual lane and the test data for that test are displayed, recorded and stored in the system and shown on the digital read out..